The Company
ACS Dobfar is a Multinational Company focused on the bulk production of Active Pharmaceutical Ingredients and Finish Dosage Forms.
The company includes fermentation facilities, bulk chemical synthesis facilities, pharmaceutical factories that conform to GMP and FDA rules.
It is present in Europe (Italy, Switzerland, Romania), Brazil and Korea.
R&D Activities
About 40 people work in the R&D Department, skilled in different “fields”, such as analytical chemistry, fermentation, molecular biology, chemical synthesis and scale-up for mass production.
Company's three main technology areas
- CHEMICAL: Chemical Synthesis
(antibacterials: penicillins, cephalosporins, carbapenems and aminoglycoside).
- BIOTECH: Fermentation, downstream purification,
biocatalisis
and molecular biology.
- ASEPTIC PRODUCTION: Sterile products, crystallisation and lyophilization.
Services provided for custom synthesis and Commercial scale manufacturing:
Area 1 - CHEMICAL
- Chemical process research
- Process optimisation on laboratory‑ pilot‑ and commercial scale
- Analytical protocols development
- Impurities’ identification and preparation
- Crystallisation and polymorphism studies
Area 2 - BIOTECH
- Process fermentation research (bacteria, fungi, yeasts)
- Strain improvement
- Recombinant DNA technologies
- Fermentation capacity from flasks to 120.000 litres
- Tangential flow membrane for nano‑ ultra‑and micro‑ filtration
- Column chromatography capacity up to 70.000 litres
- Enzyme purification and immobilization
Area 3 - ASEPTIC PRODUCTION
- Bulk sterile product crystallisation
- Bulk sterile product lyophilization
